An eight-week, randomized, double-blind, multi-center, active-controlled, parallel group study to evaluate the safety and efficacy of an aliskiren based regimen compared to a lisinopril based regimen ...

Update Il y a 4 ans
Reference: EUCTR2004-001060-50

An eight-week, randomized, double-blind, multi-center, active-controlled, parallel group study to evaluate the safety and efficacy of an aliskiren based regimen compared to a lisinopril based regimen in patients with uncomplicated severe hypertension

Woman and Man

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Extract

evaluate the overall safety of a regimen of aliskiren 150 mg potentially titrated to 300 mg O.D. with potential addition of hydrochlorotiazide (HCTZ) compared to a regimen of lisinopril 20 mg potentially titrated to 40 mg O.D. with potential addition of HCTZ in patients with uncomplicated severe hypertension (MSDBP ≥ 105 mmHg and < 120 mmHg)


Inclusion criteria

  • Hypertension