A PROSPECTIVE, MULTI-CENTRE, RANDOMISED, DOUBLE-BLIND COMPARISON OF INTRAVENOUS DEXMEDETOMIDINE WITH MIDAZOLAM FOR CONTINUOUS SEDATION OF VENTILATED PATIENTS IN INTENSIVE CARE UNIT

Mise à jour : Il y a 4 ans
Référence : EUCTR2006-006031-50

Femme et Homme

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Extrait

The study has hierarchical co-primary objectives to demonstrate that: • Firstly: dexmedetomidine is at least as effective as sedation with midazolam and daily sedation stops, in maintaining a target depth of sedation in ventilated patients in intensive care unit (ICU) • Secondly: use of dexmedetomidine, compared with sedation with midazolam and daily sedation stops, reduces the duration of mechanical ventilation in ventilated patients in ICU


Critère d'inclusion

  • Patients requiring mechanical ventilation and sedation in ICU