Pembrolizumab (MK-3475) in High Risk Non-muscle Invasive Bladder Cancer (NMIBC) Patients Unresponsive to Bacillus Calmette-Guerin (BCG) Therapy

Update Il y a 4 ans
Reference: EUCTR2014-004026-17

Woman and Man

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Extract

Objective 1: To evaluate anti-tumor activity of pembrolizumab (MK-3475), with regards to absence of high risk NMIBC or progressive disease, as determined by cystoscopy, cytology, biopsy (if applicable) and radiologic imaging by central pathology and radiology review. Objective 2: To evaluate anti-tumor activity of pembrolizumab (MK-3475) in PD-L1 positive subjects with regards to absence of high risk NMIBC or progressive disease, as determined by cystoscopy, cytology, biopsy (if applicable) and radiologic imaging by central pathology and radiology review.


Inclusion criteria

  • Non-Muscle Invasive Bladder Cancer (NMIBC)