Evaluation of the pharmacodynamic effect of the combination of Sildenafil and Riociguat on blood pressure and other safety parameters

Update Il y a 4 ans
Reference: EUCTR2010-018863-40

Woman and Man

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Extract

To evaluate the effect of 1, 1.5, 2, and 2.5 mg riociguat tid (dose titration) administered simultaneously with sildenafil on blood pressure in subjects with symptomatic pulmonary arterial hypertension.


Inclusion criteria

  • pulmonary arterial hypertension