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Extrait
To evaluate the safety, tolerability and recommended dose of abiraterone acetate administered orally, by continuous once-daily administration in patients with HRPC. To determine the effect of abiraterone acetate on the pituitary-adrenal-gonad endocrine axis and on adrenal hormones by evaluating serum levels of testosterone and its precursors. To evaluate the efficacy of abiraterone acetate in HRPC at recommended dose.
Critère d'inclusion
- Hormone refractory prostate cancer