Woman Man
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Extract
Background and study aims Evidence from the last influenza pandemic in 2009 showed that pregnant women were particularly vulnerable to severe infection. The aims of this study are, in a future influenza pandemic, to estimate the incidence of hospitalisation with pandemic-type influenza in pregnancy, and to describe the outcomes of pregnancy particularly in relation to specific treatments and according to whether women have received influenza immunisation. Who can participate? We anticipate collecting anonymous data on approximately 500 women with influenza in pregnancy in a future pandemic. What does the study involve? This study will collect anonymous data only. The cohort of pregnant women infected with influenza will be identified through the UK Obstetric Surveillance System (UKOSS) network of nominated reporting clinicians in each consultant maternity unit in the UK. Doctors and midwives will be asked to report anonymous details of pregnant women with confirmed pandemic influenza admitted to their unit. Each month throughout the study, the information collected will be analysed to describe the pregnancy and other outcomes for women and their babies and to describe their treatment. These data will be compared with previously collected information about women who do not have influenza in pregnancy. These analyses will be used to develop guidance for prevention and treatment during the pandemic. What are the possible benefits and risks of participating? There will be no benefit to individual women of inclusion of their anonymous data in the study. However, the information will be used to improve care for women and babies in the future. This study will collect anonymous data only, after women have been admitted to hospital and treated. There are thus no risks to participants. Where is the study run from? The study will run from the National Perinatal Epidemiology Unit, University of Oxford. When is the study starting and how long is it expected to run for? The study was funded in 2012, but will only be activated in the event that there is a new influenza pandemic. Who is funding the study? Funding has been provided by the National Institute for Health Research Health technology Assessment programme (NIHR HTA). Who is the main contact? Professor Marian Knight [email protected]
Inclusion criteria
- Pandemic influenza in pregnancy