A Randomized, Double Blind, Placebo Controlled Study of the Efficacy and Safety of Angiotensin Therapeutic Vaccine (ATV) in Patients With Mild to Moderate Hypertension

Update Il y a 4 ans
Reference: EUCTR2008-001001-41

Woman and Man

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Extract

The Primary efficaccy objective of this study is to determine if immunization with ATV is effective in reducing mean daytime DBP measured by ambulatory blood pressure monitoring (ABPM) in subjects with mild to moderate hypertension.


Inclusion criteria

  • Men and women, 35-70 years old with mild to moderate Hypertension as classified by the British Hypertension Society (BHS) Guidelines - BHS-IV based on the following crietia of sitting blood pressure measured by spygomanography for patienst without diabetes or renal dysfunction: Grade 1 (mild): Systolic BP 140-159 mmHG and Diastolic BP of 90-99 mmHg Grade 2 (moderate): Systolic BP 160-179 mmHg and Diastolic BP 100-109 mmHg

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