Extract

Background and study aims Over the last decade insulin delivery and blood glucose monitoring have evolved facilitating better glucose control. Continuous Subcutaneous Insulin Infusion (CSII) and Continuous Glucose Monitoring (CGM) sensors combined with an insulin delivery algorithm results in a closed loop system: an artificial pancreas. The aim of this study is to test the efficacy of a portable closed loop system first in the clinical research unit directly followed by testing at home. Who can participate? All adults diabetes mellitus (DM) type 1 treated with insulin pump What does the study involve? All participants will wear the artificial pancreas that will be compared to regular insulin pump use. What are the possible benefits and risks of participating? Benefits: This study will provide insight in glucose metabolism Risk: hyperglycemia (high blood sugar) or hypoglycemia (low blood sugar) Where is the study run from? Academic Medical Center Amsterdam When is the study starting and how long is it expected to run for? Study started in January 2012 and will run till March 2013 Who is funding the study? Academic Medical Center Amsterdam Who is the main contact? AC van Bon [email protected]

Inclusion criteria

• Diabetes mellitus type 1 treated with insulin pump

Links

• isrctn
• ictrp