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Treatment Strategies in Patients with Type 2 Diabetes Mellitus Not Achieving Glycemic Control while on Therapy with Premixed Insulin Analogues and Metformin: A Comparison of Insulin Lispro MM Intensi...

Mise à jour : Il y a 4 ans
Référence : EUCTR2006-003076-35

Treatment Strategies in Patients with Type 2 Diabetes Mellitus Not Achieving Glycemic Control while on Therapy with Premixed Insulin Analogues and Metformin: A Comparison of Insulin Lispro MM Intensive Mixture Therapy with Progressive Dose-Titration of Insulin Lispro LM or Biphasic Insulin Aspart 30/70

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Extrait

The primary objective of this study is to compare efficacy of two insulin treatment strategies in patients with type 2 diabetes who have inadequate glycemic control while treated with combination of premixed insulin analogue formulations (insulin lispro LM or biphasic insulin aspart 30/70) BID and metformin: • the proposed strategy of upgrading treatment to insulin lispro MM/LM intensive mixture therapy in combination with metformin and • the strategy of progressive dose titration of insulin analogue formulations BID combined with metformin, lifestyle and dietary intervention. This strategy reflects current common clinical practice.

Critère d'inclusion

  • Type 2 diabetes mellitus

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