Maternal, uteroplacental and fetal haemodynamic effect of Nicardipine in severe pre-eclampsia

Mise à jour : Il y a 4 ans
Référence : EUCTR2007-000727-17

Femme Homme

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Extrait

To investigate in detail the haemodynamic effects of antihypertensive treatment with Nicardipine of a hypertensive crisis in patients with severe pre-eclampsia. The effects will be investigated by maternal cardiac ultrasound and doppler ultrasound of the uteroplacental and fetal circulation.


Critère d'inclusion

  • Hypertensive crisis in patients with severe pre-eclampsia needs to be treated to prevent maternal and fetal complications. The maternal, uteroplacental and fetal haemodynamic respose to antihypertensive treatment with Nicardipinehydrochloride will be evaluated in detail by materal echocardiography and fetal doppler ultrasound as well as by the effect on plasma Brain Natriuretic Peptide concentration (BNP) and parameters of the Renin- Angiotensin- Aldosterone system (RAAS)

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