Efficacy of Once-Weekly Exenatide versus Once or Twice Daily Insulin Detemir in Patients with Type 2 Diabetes Treated with Metformin Alone or in Combination with Sulphonylurea

Mise à jour : Il y a 4 ans
Référence : EUCTR2009-010830-23

Femme et Homme

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Extrait

The primary objective of this study is to test the hypothesis that exenatide QW given once weekly for 26 weeks is superior to a titration of insulin detemir, given once or twice daily (titrated to reach a target of pre-breakfast and pre-dinner glucose concentrations of <5.5 mmol/L) when given for 26 weeks in the treatment of patients with type 2 diabetes not adequately controlled using OAD therapy. The primary efficacy measure will be assessed by the proportion of patients on each therapy who have achieved HbA1c concentration ≤7.0% with weight loss (≥1.0 kg) at endpoint.


Critère d'inclusion

  • diabetes