Extrait

to measure concentrations of cefpirome and moxifloxacin in abscess fluid and abdominal cysts; describe the concentration time-curve of these agents in pus; Individual pharmacokinetic parameters will be determined for abscess (cyst) fluid after a single dose and at steady state: AUC, AUC0-12/24h, Cmax, Tmax, t1/2ß, Cav(ss); define the therapeutic potential of cefpirome and moxifloxacin in the treatment of severe bacterial infections going ahead with abscess formation and infected abdominal cysts.

Critère d'inclusion

• Abscess or abdominal cyst

Liens

• ictrp
• euctr