A Randomized, Double-Masked, Placebo-Controlled, Multicenter, Phase 2 Study to Evaluate the Safety and Renal Efficacy of LY2382770 in Patients with Diabetic Kidney Disease due to Type 1 or Type 2 Diab...

Mise à jour : Il y a 4 ans
Référence : EUCTR2010-020404-29

A Randomized, Double-Masked, Placebo-Controlled, Multicenter, Phase 2 Study to Evaluate the Safety and Renal Efficacy of LY2382770 in Patients with Diabetic Kidney Disease due to Type 1 or Type 2 Diabetes

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Extrait

Primary objective is to determine if LY2382770, administered monthly for 1 year is more effective than placebo at slowing the progression of diabetic kidney disease in patients treated with angiotensin-converting enzyme inhibitor (ACEi) or an angiotensin II receptor blocker (ARB) administered monthly by subcutaneous injection for 1 year is more effective than placebo at slowing the progressive loss of kidney function, as measured by Serum Creatinine (SCr) change from baseline.


Critère d'inclusion

  • Patients with Diabetic Kidney Disease due to Type 1 or Type 2 Diabetes