A community setting study of malaria after systematic treatment of symptomatic carriers of P. Falciparum with COA566 (Coartem®)

Mise à jour : Il y a 4 ans
Référence : EUCTR2015-004461-85

Femme et Homme

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Extrait

• To evaluate at the community level whether treatment of AC of P falciparum is associated with a lower number of symptomatic malaria episodes RDT confirmed (SMRCs) per person-year over a 12 month follow-up in the infant and children population (i.e. <5 years of age) in the intervention clusters (villages) compared with the control clusters. • To evaluate whether treatment of AC of P. falciparum is associated with an improvement in hemoglobin levels after 28 days by comparing the change in hemoglobin levels from Day 1- of CSC 1 to Day 28 of CSC 1 for microscopy confirmed AC > 6 months of age in the intervention versus the control arms.


Critère d'inclusion

  • This study assessed the impact of the systematic detection by Rapid Diagnostic Test (RDT) and treatment of asymptomatic carriers of malaria parasites (P. falciparum) with COA566 on the number of clinical malaria cases in children less than 5 years of age and the improvement of hemoglobin levels in the overall population

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