Extrait

Background and study aims Overweight and obese adults are now more common, and this is associated with diseases such as diabetes, heart disease and cancer, which puts increased pressure on the National Health Service (NHS). There is urgent need for weight loss programmes that are effective, affordable and can be delivered on a large scale via GP surgeries. Recent studies have demonstrated the short tem effectiveness of GP referral to a commercial weight loss provider. The NHS now needs information on the longer term outcomes of these programmes and the length of treatment that is most effective and gives best value for money. Who can participate? Men and women, aged 18 and over, who have a Body Mass Index (BMI) of 28 kg/m2 and who have been identified by a participating GP practice as likely to benefit from weight loss. Participants must be willing and able to participate in the weight loss group they are assigned to, and to attend measurement appointments with the research team. What does the study involve? Participants will be randomly assigned to one of three treatment programmes: 1. Referral to Weight Watchers for 12 weeks, free of charge. 2. Referral to Weight Watchers for 12 months, free of charge. 3. Standard information with periodic weighing and feedback, delivered by the research team. Participants will attend 4 appointments over the 2 years, during which measures including weight, body composition, waist circumference and blood pressure will be taken. Participants will also be asked to complete questionnaires measuring psychological factors, quality of life, and health care usage. The research team will also ask the participants if they are willing to provide additional blood samples at the initial visit and at 1 year measure risk factors for diabetes and cardiovascular disease. What are the possible benefits and risks of participating? Free advice and support will be given to assist in following a healthy diet and losing weight. There is little risk in taking part in this trial. If blood is taken, there may be minor discomfort or bruising, but this will be monitored carefully by trained professionals. Where is the study run from? MRC Human Nutrition Research, Cambridge, in collaboration with University of Oxford, University of Liverpool, University of East Anglia, University of Cambridge, and the National Heart Forum. When is the study starting and how long is it expected to run for? Recruitment will take place between October 2012 and October 2013. All participants will be followed up for 2 years from their initial assessment. Who is funding the study? National Prevention Research Initiative grant and Weight Watchers International as part of an MRC Industrial Collaboration Award. Who is the main contact? Dr Amy Ahern [email protected]

Critère d'inclusion

• Overweight and obesity

Liens

• isrctn
• ictrp