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Kusajili – Centralise les essais cliniques mondiaux
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Pays: Lithuania,Czech Republic,France,United Kingdom,South Africa,Austria,Israel,Poland,Belgium,Italy
nct
MAJ Il y a 5 ans
Oral Topotecan Versus Intravenous Docetaxel In Pretreated, Advanced Non-Small Cell Lung Cancer
The purpose of this study is to collect information on how effective and how well tolerated an oral investigational drug is compared to a standard intravenous drug in patients with pretreated, advanced non-small lung cancer (NSCLC).
Pays
Australia
,
Austria
,
Belgium
,
Canada
,
China
,
Czech Republic
,
Denmark
,
Finland
,
France
,
Germany
,
Greece
,
Hungary
,
Israel
,
Italy
,
Latvia
,
Lithuania
,
Netherlands
,
New Zealand
,
Philippines
,
Poland
,
Portugal
,
Russian Federation
,
Singapore
,
South Africa
,
Spain
,
Switzerland
,
Taiwan, Province of China
,
Thailand
,
Turkey
,
Ukraine
,
United Kingdom
,
Organes
Aucun
Spécialités
Aucun
Essai clos aux inclusions
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nct
MAJ Il y a 5 ans
The Efficacy, Safety and Tolerability of E2007 in Levodopa Treated Parkinson's Disease Patients With Motor Fluctuations
Patients will be randomised to receive either placebo or the study drug for a period of 30 weeks, in addition to their standard Parkinsonian medications. During the first 8 weeks, the patient's levodopa doses may be adjusted if necessary by the investigator. For the remainder of the 22 weeks, all medications should be kept stable. Patients will be required to attend the clinic twice during the screening period and then a further 8 times during the treatment period. They will be required to complete home diaries where they will record their motor function. In addition, their doctor will assess their Parkinson's disease during the clinic visits. There will also be blood draws for safety and pharmacokinetic and pharmacogenomics evaluation. Following the treatment and assessment period, they will return to the clinic one month later for follow up.
Pays
Austria
,
Belgium
,
Czech Republic
,
Estonia
,
France
,
Germany
,
Hungary
,
Israel
,
Italy
,
Lithuania
,
Poland
,
Portugal
,
Serbia
,
South Africa
,
Spain
,
Sweden
,
United Kingdom
,
Organes
Aucun
Spécialités
Aucun
Essai clos aux inclusions
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