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Kusajili – Centralise les essais cliniques mondiaux
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Pays: Germany,Belgium,Lithuania,Hungary,Finland,Sweden,United Kingdom,Spain,Denmark,Greece,Netherlands
nct
MAJ Il y a 5 ans
Nilotinib in Newly Diagnosed Adult Philadelphia Chromosome & /or BCR-ABL Positive Chronic Myeloid Leukaemia in Chronic Phase
This study will assess the efficacy and safety of nilotinib in adult patients with newly diagnosed Philadelphia chromosome positive/BCR-ABL positive chronic myeloid leukaemia in chronic phase. The aim of the study is to confirm the rates of complete molecular remission (CMR) of nilotinib in newly diagnosed CML chronic phase patients in a pan-European population using the EUTOS standardized laboratories.
Pays
Austria
,
Belgium
,
Bulgaria
,
Croatia
,
Czech Republic
,
Denmark
,
Estonia
,
Finland
,
France
,
Germany
,
Greece
,
Hungary
,
Italy
,
Latvia
,
Lithuania
,
Netherlands
,
Norway
,
Poland
,
Portugal
,
Romania
,
Slovakia
,
Slovenia
,
Spain
,
Sweden
,
Switzerland
,
United Kingdom
,
Organes
Aucun
Spécialités
Aucun
Essai clos aux inclusions
Plus d'informations
nct
MAJ Il y a 5 ans
A Safety and Efficacy Study of Ustekinumab in Patients With Plaque Psoriasis Who Have Had an Inadequate Response to Methotrexate
This purpose of this study is to assess the safety of ustekinumab in psoriasis patients who receive ustekinumab following an inadequate response to methotrexate therapy. The study will provide information for doctors on how to manage the transfer from methotrexate to the biologic agent ustekinumab. The study is designed to compare two methods of transferring patients from methotrexate to ustekinumab. The two methods being compared are discontinuation of methotrexate with immediate initiation of ustekinumab versus initiation of ustekinumab with overlap and gradual dose reduction of methotrexate over 4 weeks.
Pays
Austria
,
Belgium
,
Bulgaria
,
Denmark
,
Finland
,
France
,
Germany
,
Greece
,
Hungary
,
Israel
,
Lithuania
,
Netherlands
,
Norway
,
Poland
,
Portugal
,
Slovakia
,
Spain
,
Sweden
,
United Kingdom
,
Organes
Aucun
Spécialités
Aucun
Essai clos aux inclusions
Plus d'informations
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