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Kusajili – Centralise les essais cliniques mondiaux
Résultat
de votre recherche par promoteur : Merck Serono SA - Geneva
Femme et Homme Max 99 ans
Merck Serono SA - Geneva
MAJ Il y a 4 ans
A phase III, double-blind, placebo-controlled extension trial to investigate the long-term efficacy and safety of low (50 mg/day) and high (100 mg/day) dose safinamide, as add-on therapy in subjects with early idiopathic Parkinson?s disease treated with a stable dose of a single dopamine agonist
The primary objective is to evaluate the time to first intervention of two doses of safinamide (50 and 100 mg/day) compared to placebo as add-on therapy to a single dopamine agonist.
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Essai clos aux inclusions
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Femme et Homme Max 99 ans
Merck Serono SA - Geneva, an affiliate of Merck KGaA, Darmstadt, Germany
MAJ Il y a 4 ans
A four-arm randomised, double-blind, placebo-controlled, multicentre Phase II study to evaluate the safety, tolerability and efficacy as assessed by frequent MRI measures of three doses of atacicept monotherapy in subjects with relapsing multiple sclerosis (RMS) over a 36 weeks treatment course
The primary objective of the study is to evaluate the efficacy of three doses of atacicept to reduce CNS inflammation in subjects with RMS as assessed by frequent MRI.
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Essai clos aux inclusions
Plus d'informations
Femme et Homme Max 99 ans
Merck Serono SA - Geneva
MAJ Il y a 4 ans
A phase III, double blind, placebo-controlled extension trial to investigate the long-term efficacy and safety of safinamide (50 to 100 mg/day), as add on therapy, in subjects with idiopathic Parkinson’s disease with motor fluctuations, treated with a stable dose of levodopa and who may be receiving concomitant treatment with stable doses of a dopamine agonist, an anticholinergic and/or amantadine
The primary objective is to evaluate the change from baseline to W78 in dyskinesia using the Dyskinesia Rating Scale during the “on” phase, comparing safinamide (50-100 mg/day) to placebo.
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Essai clos aux inclusions
Plus d'informations
Femme et Homme Max 99 ans
Merck Serono SA - Geneva
MAJ Il y a 4 ans
A multinational, multicenter, single visit, exploratory pharmacogenetic trial and long-term follow-up of the PRISMS (Prevention of Relapses and Disability by Interferon beta-1a Subcutaneously in Multiple Sclerosis) trial
To analyze the association between single nucleotide polymorphism (SNP) markers and treatment response. Treatment response is based on the Expanded Disability Status Scale (EDSS) progression and relap...
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Organes
Aucun
Spécialités
Aucune
Essai clos aux inclusions
Plus d'informations