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Kusajili – Centralise les essais cliniques mondiaux
Résultat
de votre recherche par promoteur : Grünenthal GmbH
Femme et Homme Max 99 ans
Grünenthal GmbH
MAJ Il y a 4 ans
A randomised, 2-arm, parallel group study assessing efficacy and tolerability of titrated transdermal buprenorphine in patients with moderate to severe chronic non malignant pain
To assess the efficacy and tolerability of a titrated divisible buprenorphine transdermal patch in comparison to non-titrated buprenorphine transdermal patch over 4 weeks in opioid naïve patients with...
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Essai clos aux inclusions
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Homme Max 99 ans
Grünenthal GmbH
MAJ Il y a 4 ans
Comparison of blood concentrations of tapentadol from 4 prolonged release formulations (3 granule formulations and 1 tablet formulation) in healthy adult subjects
The primary objective of the trial is to assess the pharmacokinetics and relative bioavailability of tapentadol following administration of 3 prototype tapentadol PR granule formulations (test formula...
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Essai clos aux inclusions
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Femme Max 99 ans
Grünenthal GmbH
MAJ Il y a 4 ans
A randomized, double-blind, parallel-arm, placebo- and comparator-controlled trial of the efficacy and safety of multiple doses of immediate-release (IR) CG5503 for postoperative pain following abdominal hysterectomy
The primary objective is to demonstrate the efficacy and safety of multiple-dose application of three different oral doses of CG5503 IR compared to placebo and to assess safety and tolerability of CG5...
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Essai clos aux inclusions
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Femme et Homme Max 99 ans
Grünenthal GmbH
MAJ Il y a 4 ans
Use of intravenous tapentadol solution for injection for pain after surgery in children from newborn to less than 2 years old, including preterm babies. Uso de tapentadol en solución inyectable intravenosa para el dolor postquirúrgico en niños desde el nacimiento hasta menos de 2 años, incluidos los bebés prematuros
The primary objective of the trial is to collect serum concentration data of tapentadol and its major metabolite tapentadol-O-glucuronide after the administration of a single dose of intravenous tapen...
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unknown
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Femme Max 99 ans
Grünenthal GmbH
MAJ Il y a 4 ans
A clinical trial to find out whether GRT6010, when instilled into the bladder, eases pain and functional symptoms, is safe, and is tolerable in adults with bladder pain syndrome Badanie kliniczne mające na celu sprawdzenie, czy preparat GRT6010 podawany dopęcherzowo zmniejsza ból i objawy czynnościowe, jest bezpieczny i dobrze tolerowany u osób dorosłych z zespołem bolesnego pęcherza
Evaluate the efficacy of intravesical instillation of GRT6010 on pain.
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unknown
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Femme et Homme Max 99 ans
Grünenthal GmbH
MAJ Il y a 4 ans
A randomized withdrawal, active- and placebo-controlled, double-blind, multi-center Phase III trial assessing safety and efficacy of oral CG5503 PR in subjects with moderate to severe chronic malignant tumor-related pain
The primary objective of this trial is to evaluate the safety and efficacy of orally administered CG5503 PR tablets BID over 4 weeks (Maintenance phase) in subjects with moderate to severe chronic mal...
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Essai clos aux inclusions
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Femme et Homme Max 99 ans
Grünenthal GmbH
MAJ Il y a 4 ans
Lidocaine/diclofenac epolamine patch (GRT7019) Phase II proof-of-concept trial in patients with chronic pain due to knee osteoarthritis
Evaluation of the analgesic efficacy of a once daily application of GRT7019 for 4 weeks compared to placebo.
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unknown
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Femme et Homme Max 99 ans
Grünenthal GmbH
MAJ Il y a 4 ans
A multicenter, open-label trial to assess cognitive and psychomotor performance as surrogate parameters for driving ability under stable long term treatment with tapentadol hydrochloride prolonged-release tablets in subjects with chronic low back pain or osteoarthritis of the knee
To evaluate the cognitive and psychomotor performance as measured by a validated methodology (Vienna Test System – Traffic Plus) based on a global judgment as the key outcome surrogate parameter for d...
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Essai clos aux inclusions
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Femme et Homme Max 99 ans
Grünenthal GmbH
MAJ Il y a 4 ans
A Randomized Double-Blind, Placebo- and Active-Control, Parallel-arm, Phase III Trial with Controlled Adjustment of Dose to Evaluate the Efficacy and Safety of CG5503 Prolonged-Release (PR) in Subjects with Moderate to Severe Chronic Pain Due to Osteoarthritis of the Knee
The primary objective of the trial is to evaluate the efficacy and safety of orally administered CG5503 PR (base) at doses of 100-250 mg twice daily in subjects with moderate to severe chronic pain fr...
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Essai clos aux inclusions
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Femme et Homme Max 99 ans
Grünenthal GmbH
MAJ Il y a 4 ans
Efficacy and safety of intravenous neridronic acid in CRPS-I
To demonstrate the efficacy of neridronic acid, versus placebo, in treatment of pain associated with CRPS-I.
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